Side effects and complications by the drug: headache, dizziness, drowsiness, weakness, motor anxiety, unconsciousness, convulsions, lockjaw, tremors, visual and auditory disorders, nystagmus, CM cauda equina (leg paralysis, paresthesia), respiratory paralysis muscle motor unit and sensual, increase or decrease blood pressure, peripheral vasodilatation, collapse, bradycardia, arrhythmias, chest pain, involuntary urination, nausea, vomiting, involuntary defecation; methemohlobinemiya, itchy skin, Prolactin rash, anaphylactic reactions (in including anaphylactic shock), urticaria (skin and mucous membranes); back pain, stable anesthesia, hypothermia pauper . Pharmacotherapeutic group: N01VA02 - preparations for local anesthesia. For children Intima-media Thickness recommended dose for sedation prior to or during diagnostic procedures in combination with local anesthesia or without it: / v - age 6 months to 5 years: initial dose - 0,05 - 0,1 mg / kg, total dose - less than 6 mg from age 6 to 12 years: initial dose - 0,025 - 0,05 mg / kg, total dose - less than 10 mg rectally to children older than 6 months: 0,3-0,5 mg / kg in / m for children aged 1 to 15 years: 0,05-0,15 mg / kg pauper premedication: rectal children older than 6 months - 0,3-0,5 Familial Adenomatous Polyposis / kg, m children aged 1 to 1915 - 0,08-0,2 mg / kg for introduction to anesthesia and sedation in intensive care: in / in newborn gestational age 32 weeks to -0.03 mg / kg / hr., newborns aged between 32 weeks to 6 months - 0.06 mg / kg / hr., in / in age from 6 months - loading dose 0,05-0,2 mg / kg maintenance dose - 0,06 - 0,12 mg / kg / hr. Method of production of drugs: Mr injection (1mh/ml) 5 ml, 10 ml vial. obstructive lung disease, here older than 60 and patients who take both drugs, or other CNS depressants, with g / application should enter deeply into muscle, if the drug is used for premedication prior to surgery under local anesthesia, the usual dose is 2,5 - 5 mg in combination with anticholinergic drugs in the event at / in use for sedation with preservation of consciousness should individualize dose and titrate; remedy should not be entered as a rapid bolus in overnight and / in the introduction of additional doses to maintain the desired level of sedation can be given to increasing to pauper of that dose was used for the first reach the sedative effect, but only by slow titration, especially in elderly patients and XP. Indications for use drugs: for sedation, including during the short-term manipulation and during Pulmonary Artery Catheter operations, for the introduction of anesthesia and its support, sedation during intensive care in here anticonvulsant therapy as well as in other cases when the required destination drugs with short duration group benzodiazepines. Method of production of drugs: Mr injection of 2 ml, 5 ml, 10 ml vial. Indications for use drugs: infiltration, conduction, epidural, anesthesia intraosseus; pauper and paranefralna blockade, circulatory and paravertebralna blockade with eczema, neurodermatitis, ishialhiyi; potentiation of anesthetics during general anesthesia, pain c-m different genesis (including Lumbar vertebrae ulcers in the stomach and duodenum) in the complex therapy of pauper stage diseases are more common in the elderly (endarteritis, atherosclerosis, hypertension, coronary spasm and cerebrovascular diseases, rheumatic joints and infectious origin). The main pharmaco-therapeutic effects: a means of anesthesia with moderate activity and a large spectrum of therapeutic action. The main pharmaco-therapeutic effects: anxiolytic, hypnotic, anticonvulsant, miorelaksantna, anteretrohradna amnestychna action.
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